April 18, 2005

Genistein May Help Overcome Cisplatin-Resistance in Ovarian Cancer

Dr. Solomon, from the Barbara Ann Karmanos Cancer Institute at WSU, found that the addition of genistein, a soy isoflavone, alone to cisplatin-sensitive and cisplatin-resistant human epithelial ovarian cancer cells had significant cytotoxic effects. Dr. Solomon said additional in-vitro and animal studies on the effects of genistein in platinum-resistant cancers are planned, \"which can easily and quickly be translated into human trials."

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